Amercare A2 Pharmacy Isolators provide a fully enclosed, safe environment for the handling of sensitive or hazardous materials during sterile preparation and aseptic pharmaceutical workflows.
At Amercare, we design and manufacture for our customers standard configuration and custom pharmaceutical isolators. Developed to provide controlled conditions, sterile environments and optimised efficiency to support preparation of pharmacy products and safe aseptic filling.
Pharmaceutical isolators are used for compounding hazardous drugs, preparing sterile products with complete protection against contamination, handling sensitive biological materials, and supporting aseptic pharmacy workflows, including automated processes.
Amercare offers a range of pharmacy isolators, with the flexibility to configure systems to best suit your workflow and application requirements.
| Laminar flow isolators | Turbulent flow isolators |
|---|---|
| Provide a unidirectional stream of clean air to the work zone and continuously sweep contaminants away. They are ideally suited to applications where product sterility is the highest priority. | Introduce clean air then circulates it using a mixed airflow pattern that dilutes and removes airborne contaminants, thus reducing concentration within the work zone. |
| Negative pressure isolators | Positive pressure isolators |
|---|---|
| Protect the operator and environment by preventing contaminants from escaping, making them suitable for handling hazardous or potent compounds. | Protect the product from external contamination, making them ideal for sterile manufacturing and aseptic processing applications. |
| Market-leading quality |
Fully welded high-grade 3mm 316 stainless steel construction with satin bead blasted and passivated finishes |
Included |
| Clean air environments |
Equivalent to EU GMP Grade A and ISO 14644-1 Class 5 |
Included |
| High-efficiency filtration |
HEPA filtered inlet and extract air delivers 99.995% efficiency at 0.3 microns (MPPS) |
Included |
| Gas/odour filtration |
Additional carbon filtration tailored to application |
Optional |
| Controlled product transfer |
Timed interlock transfer chamber control ensures controlled, sequential door operation and defined dwell times |
Included |
| Power loss protection |
Battery backup maintains essential functions including door operation, interlocks and airflow monitoring |
Included |
| Superior corrosion resistance |
Constructed from high-grade 316 stainless steel with aluminium and plastic external surfaces |
Included |
| Accessible cleaning |
Fully accessible external surfaces, with all internal areas accessible through the glove ports |
Included |
| Contain spillages |
Seamless internal bases with no air grilles, cavities, or inaccessible areas |
Included |
| Accessible testing |
Accessible test points for routine maintenance and validation protocols |
Included |
| Safe filter change |
Prevent exposure during filter changes with safe change exhaust filters |
Included |
| Maintain room pressure |
Prevent disruption to surrounding environments during testing with an integrated bypass valve |
Optional |
| Bio-decontamination |
Gassing connections, gassing doors and a range of hydrogen peroxide vaporisation (HPV) systems available |
Optional |
| Enhanced validation |
Further testing packages available including DQ, FAT, IQ, OQ and gas cycle development (optional) |
Included |
| Leak integrity validation |
Integrated automated pressure decay testing with out-of-hours function (optional turbulent) |
Included |
| Real-time status |
Microprocessor-based control system monitors and displays isolator status in real-time |
Included |
| Safe operation assurance |
A digital alarm system monitors key functions and provides immediate visual and audible alerts |
Included |
| Continuous environmental insight |
Real-time continuous particle monitoring via an integrated isokinetic sampling head inside the chamber |
Optional |
| Full monitoring capability |
Connections available for gas sterilisation, viable and non-viable air sampling, biological sampling and bespoke requirements
|
Configurable |
| Data traceability |
Automatic data recording and optional printout functionality |
Optional |
| Facility-wide monitoring and control |
Connect seamlessly with BMS and EMS platforms |
Optional |
| Save energy costs |
Low-energy EC fans and LED lighting |
Included |
| Comfortable operation |
Electrical and manual height-adjustable base frames, adjustable footrests and unobstructed knee space |
Included / Configurable |
| Seamless process integration |
Internal service connections for mains power, data, compressed air, gases, fluid feedline hubs and equipment |
Included / Configurable |
| Integrated equipment |
Space for or fully integrated process equipment, sterility testing, automation equipment etc |
Optional |
| Simplified product transfer |
Lightweight innovative vacuum seal doors with foot-operated release, wide clear openings, and angled transfer chamber bases |
Included |
| Organised tools & materials |
Integrated hanging rails, hooks, trays, and shelving
|
Optional |
| Visible processes |
CCTV, display monitors and intercom systems |
Optional |
| Airflow | Unidirectional | Turbulent | |
| Chamber pressure | Negative | Positive | |
| Extract | Total loss | Thimble | Recirculating |
| Glove ports | 2 | 3 | 4 |
| Glove port size | 250mm standard | 200mm optional |
| Configuration | Length (mm) | Depth (mm) | Max Height (mm) |
|---|---|---|---|
| 2 Glove Throughflow | 1840 | 740 | 1540 – 1840 (+ 150mm for recirculating extract) |
| 3 Glove Throughflow | 2040 | 740 | 1540 – 1840 (+ 150mm for recirculating extract) |
| 4 Glove Throughflow | 2440 | 740 | 1540 – 1840 (+ 150mm for recirculating extract) |
Amercare supports the ongoing performance, reliability and safe operation of all isolators with a range of in-stock consumables, replacement components, planned servicing, and available technical support. This ensures consistent operation, reduced downtime, and long-term support throughout the lifecycle of your system.
Tailor your isolator to your specific requirements with our complimentary design service.
Arrange your free consultation and no-obligation quote today.