Gassing Isolators with Integrated Bio-Decontamination

Amercare Gassing Isolators (also known as VHP gassing isolators or vaporised hydrogen peroxide isolators) are designed to support Annex 1-aligned aseptic processes requiring validated automated bio-decontamination. Combining high-performance airflow control and containment with vaporised hydrogen peroxide (VHP) decontamination, they help maintain product integrity, operator protection and environmental control.

Gassing isolators can be supplied with a fully integrated VHP generator or configured for connection to an external freestanding unit, depending on facility and process requirements. Each isolator delivers closed-loop validated gassing cycles across individual sections or the entire system, allowing complete or targeted bio-decontamination to suit your workflow. High air change rate entry chambers enable rapid material transfer and validated gassing cycles in as little as 20 minutes, helping to maintain workflow efficiency while supporting contamination control and regulatory compliance.

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✓ Energy Efficient

✓ Market-Leading Quality

✓ ISO 14644-1 Class 5

✓ EU GMP Grade A

Amercare Isolators are fully configurable to your requirements through our complementary design service.

Gassing Isolators Tailored to Your Operations

Integrated Bio-Decontamination

Supports annex 1-aligned processes

Unidirectional Airflow

Delivers clean air across the work zone

Gassing isolators are engineered to support critical processes where contamination control and validated, repeatable bio-decontamination are essential for safe and compliant operations. Whether you require a standard configuration or a fully tailored solution, our complimentary design service ensures your isolator is engineered in the optimal configuration for your facility and workflow.

They are widely used across applications including cell therapy, sterility testing, cytotoxic dispensing and centralised intravenous admixing (CIVAS), and can be fully adapted to meet your exact process and compliance requirements.

A wide range of configurations, accessories and integrated equipment options are available, allowing the system to be built around how your team works. This tailored approach improves operational efficiency, supports consistent decontamination performance and reduces workflow disruption by aligning equipment design with real-world use.

Gassing Isolator Options

Amercare x Bioquell (Ecolab) Gassing Isolator

Amercare can supply isolators with the Bioquell (Ecolab) Port II and L-4 VHP generators. The L-4 generator provides a reliable and robust solution for vapourised hydrogen peroxide (VHP) generation, while the Port II offers higher capacity with rapid cycle capability, achieving batch decontamination in as little as 25 minutes. Learn more

isolator with integrated biodecontamination to support annex 1

Amercare x Steris Gassing Isolator

Amercare can supply isolators with STERIS VHP systems, including the VHP Flex™ standalone biodecontamination unit or the integrated M100-S system. The VHP Flex™ is a compact, portable solution for flexible deployment, while the M100-S provides a fully integrated system for automated decontamination. Learn more

Key Gassing Isolator Features

Fully Accessible Process Chamber

A hinged front panel allows for large items of equipment such as compounders, stirrers, balances etc to be moved in and out of the Process Section.

Efficient Product Loading

Configurable racking and trolley options enable efficient presentation of loads both to the isolator transfer chambers and to the Port II’s hydrogen peroxide vapour chamber.

Controlled Waste Disposal

Lockable waste chutes and rigid pods or heat sealable bagging out systems enable the safe and controlled disposal of waste and contaminated materials.

Standard Configuration Options

Glove ports	3	4
Chamber pressure	Negative	Positive
Transfer chamber	Standard	Rapid transfer
Entry chamber	Standard	Gloved
Extract	Total loss / thimble	Recirculating
Gas generator	Fully integrated	Freestanding connections

Technical Information

Transfer Chamber Air Quality	Type D or E, High Flow Turbulent ECGMP Grade A
Carcass Materials	Grade 316L Stainless Steel
Main Chamber Pressure (+ve)	+100Pa (+ve) or -250Pa (-ve)
Transfer Chamber Pressure (+ve)	+70Pa (+ve) or -300Pa (-ve)
Leak Classification	ISO 14644 Class 3
Main Chamber Inlet Filter	HEPA Grade H14
Main Chamber Extract Filter	HEPA Grade H14
Transfer Chamber Inlet Filter	HEPA Grade H14
Transfer Chamber Extract Filter	HEPA Grade H14
Secondary Extract Filter	HEPA Grade H14
Air Extract Rate	0.08m³/s for main chamber plus 0.04m³/s for each transfer chamber.
Lighting	Low Energy lighting to provide glare free minimum 750lux at the working position.
Sound level	Less than 65DbA at the working position.
Power supply	Either 240v or 110v AC
Service requirements	Electrical supply & ducted extract with remote fan.

Supporting You and Your Isolator
for Life

Amercare supports the ongoing performance, reliability and safe operation of all isolators with a range of in-stock consumables, replacement components, planned servicing, and available technical support. This ensures consistent operation, reduced downtime, and long-term support throughout the lifecycle of your system.

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Tailor your isolator to your specific requirements with our complimentary design service.

Arrange your free consultation and no-obligation quote today.